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ZCRB1 antibody

Anti-ZCRB1 antibody used in Western Blot (WB). GTX85274

Cat No. GTX85274

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ELISA
Reactivity Human, Mouse, Rat
Package
100 μg ($339)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

25 kDa. ( Note )

Positive Control

Raji Cell Lysate(GTX27908)
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

ZCRB1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ZCRB1.The immunogen is located within the last 50 amino acids of ZCRB1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

zinc finger CCHC-type and RNA binding motif containing 1 , MADP-1 , MADP1 , RBM36 , SNRNP31 , ZCCHC19

Cellular Localization

nucleoplasm

Background

ZCRB1 is a nuclear protein first identified in a differential display screen involving morphine-dependence-related genes. Its expression is increased following morphine treatment and has been observed to be elevated in HepG2 cells. ZCRB1 contains a CCHC-type zing finger RNA-binding motif and can interact with the DBA-binding domain of the stem cell regulator C/EBP transcription factors. ZCRB1 was identified as one of the protein components of U11/U12 snRNPs, which are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron, suggesting ZCRB1 may play a key role in U12-type splicing.

Database

DATA IMAGES
Anti-ZCRB1 antibody used in Western Blot (WB). GTX85274

GTX85274 WB Image

WB analysis of Raji cell lysate using GTX85274 ZCRB1 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

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Package List Price ($)
$ 339