GeneTex
  • Country / Location Selection

United States (US)

beta Tubulin 4 antibody [ONS.1A6]

Cat No. GTX11315

Host Mouse
Clonality Monoclonal
Clone Name ONS.1A6
Isotype IgG1
Application WB, ICC/IF, IHC-P, ELISA
Reactivity Human, Mouse, Rat, Bovine, Hamster, Chicken
Package
100 μl ($319)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:400
ICC/IF Assay dependent
IHC-P Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

Positive Control

MCF7
PROPERTIES

Form

Liquid

Buffer

Ascites

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

synthetic peptide corresponding to the C-terminal sequence of β-tubulin isotype IV, conjugated to BSA.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

tubulin beta 4A class IVa , DYT4 , TUBB4 , beta-5

Cellular Localization

Cytoplasm, cytoskeleton

Background

The major building block of microtubules is tubulin, an intracellular cylindrical filamentous structure that is present in almost all eukaryotic cells. Except in the simplest eukaryotes, tubulin exists in all cells as a 100 kD protein, a heterodimer of two similar but not identical polypeptides, designated alpha and beta, that assembles into microtubules. Both alpha and beta tubulins consist of various isotypes. For beta tubulin, six evolutionarily conserved isotypes were identified (designated beta I-beta VI). Beta IV exists as two subtypes in mammals, differing from each other at 10 positions. beta IVa is brain specific, whereas beta IVb is ubiquitous, and both appear to be constitutive. The detection, localization and characterization of proteins involved in microtubule function is fundamental to the understanding of mitosis, meiosis, organellar and flagellar movement, intracellular transport, and cytoskeletal functions.

Database

Research Area

REFERENCE
There are currently no references for beta Tubulin 4 antibody [ONS.1A6] (GTX11315). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for beta Tubulin 4 antibody [ONS.1A6] (GTX11315). Be the first to share your experience with this product.
Package List Price ($)
$ 319