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hnRNP L antibody

Anti-hnRNP L antibody used in IHC (Paraffin sections) (IHC-P). GTX66652
Anti-hnRNP L antibody used in Western Blot (WB). GTX66652

Cat No. GTX66652

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($349)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:1000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

64 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.2, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 30-80 of Human hnRNP L.

Purification

Purified by antigen-affinity chromatography
From serum

Purity

> 95% (by SDS-PAGE)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

heterogeneous nuclear ribonucleoprotein L , HNRPL , P/OKcl.14 , hnRNP-L

Cellular Localization

Nucleus, nucleoplasm,Cytoplasm

Background

Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-hnRNP L antibody used in IHC (Paraffin sections) (IHC-P). GTX66652

GTX66652 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX66652 hnRNP L antibody.
Dilution : 1:100

Anti-hnRNP L antibody used in Western Blot (WB). GTX66652

GTX66652 WB Image

WB analysis of various samples using GTX66652 hnRNP L antibody.
Lane1 : MCF-7 whole cell lysate(10ug)
Lane2 : A549 whole cell lysate(10ug)
Lane3 : K562 whole cell lysate(10ug)
Lane4 : The Uterus tissue lysate of Rat(20ug)
Lane5 : The Brain tissue lysate of Mouse(40ug)
Dilution : 1:500

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf