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mGluR3 antibody

Anti-mGluR3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70719
Anti-mGluR3 antibody used in IHC (Paraffin sections) (IHC-P). GTX70719
Anti-mGluR3 antibody used in IHC (Paraffin sections) (IHC-P). GTX70719
Anti-mGluR3 antibody used in IHC (Paraffin sections) (IHC-P). GTX70719
Anti-mGluR3 antibody used in IHC (Paraffin sections) (IHC-P). GTX70719
Anti-mGluR3 antibody used in IHC (Paraffin sections) (IHC-P). GTX70719

Cat No. GTX70719

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

ICC/IF, IHC-P

Reactivity

Human, Mouse, Rat, Bovine, Hamster, Pig, Monkey, Horse
Package
25 μg ($269)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
IHC-P 16 μg/ml
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

Predict Reactivity

Rabbit, Chicken, Elephant, Gibbon, Gorilla, Lizard, Marmoset, Opossum, Orangutan, Panda, Turkey, Platypus, Zebra finch(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 16 amino acid peptide from N-terminal extracellular domain of human GRM3 / MGLUR3.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

, GLUR3 , GPRC1C , GRM3 , MGLUR3 , glutamate metabotropic receptor 3 , mGlu3 , mGluR3 , metabotropic Glutamate Receptor 3

Cellular Localization

Cell membrane

Background

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-mGluR3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70719

GTX70719 ICC/IF Image

ICC/IF analysis of HEK293 transfected with mGluR3 using GTX70719 mGluR3 antibody.

Anti-mGluR3 antibody used in IHC (Paraffin sections) (IHC-P). GTX70719

GTX70719 IHC-P Image

IHC-P analysis of brain, amygdala neurons tissue using GTX70719 mGluR3 antibody.

Anti-mGluR3 antibody used in IHC (Paraffin sections) (IHC-P). GTX70719

GTX70719 IHC-P Image

IHC-P analysis of brain, glioblastoma tissue using GTX70719 mGluR3 antibody.

Anti-mGluR3 antibody used in IHC (Paraffin sections) (IHC-P). GTX70719

GTX70719 IHC-P Image

IHC-P analysis of human brain, pituitary tissue using GTX70719 mGluR3 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-mGluR3 antibody used in IHC (Paraffin sections) (IHC-P). GTX70719

GTX70719 IHC-P Image

IHC-P analysis of human skin, melanoma tissue using GTX70719 mGluR3 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-mGluR3 antibody used in IHC (Paraffin sections) (IHC-P). GTX70719

GTX70719 IHC-P Image

IHC-P analysis of human brain, glioblastoma tissue using GTX70719 mGluR3 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf