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mGluR3 antibody

Anti-mGluR3 antibody used in IHC (Paraffin sections) (IHC-P). GTX70719

Cat No. GTX70719

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application ICC/IF, IHC-P
Reactivity Human
Package
25 μg ($319)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF Assay dependent
IHC-P 16 μg/ml
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

Predict Reactivity

Mouse, Rat, Zebrafish, Rabbit, Bovine, Hamster, Chicken, Pig, Monkey, Elephant, Gibbon, Gorilla, Horse, Lizard, Marmoset, Opossum, Orangutan, Panda, Turkey, Platypus(>80% identity)
PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 16 amino acid peptide from N-terminal extracellular domain of human mGluR3.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

glutamate metabotropic receptor 3 , GLUR3 , GPRC1C , MGLUR3 , mGlu3

Cellular Localization

Cell membrane

Background

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
Anti-mGluR3 antibody used in IHC (Paraffin sections) (IHC-P). GTX70719

GTX70719 IHC-P Image

IHC-P analysis of human brain tissue (pituitary) using GTX70719 mGluR3 antibody.
Antigen retrival : Heat-induced antigen retrieval

REFERENCE
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REVIEW
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Package List Price ($)
$ 319