United States (US)

sRANKL antibody

Anti-sRANKL antibody used in IHC (Paraffin sections) (IHC-P). GTX31300
Anti-sRANKL antibody used in Western Blot (WB). GTX31300

Cat No. GTX31300

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

35 kDa. ( Note )

Positive Control

Rat Liver Tissue Lysate(GTX27943) , Human Liver Tissue Slide , Human Liver Tissue Lysate




PBS with 0.02% sodium azide.


Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.


1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species



sRANK-L antibody was raised against a 14 amino acid synthetic peptide from near the center of human sRANK-L.The immunogen is located within amino acids 140 - 190 of sRANK Ligand.


Purified by antigen-affinity chromatography




For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.


Tnf Superfamily Member 11,Cd254,Odf,Opgl,Optb2,Rankl,Tnlg6B,Trance,Hrankl2,Sodf,Tnfsf11


This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced tra


Research Area

Anti-sRANKL antibody used in IHC (Paraffin sections) (IHC-P). GTX31300

GTX31300 IHC-P Image

IHC-P analysis of human liver tissue using GTX31300 sRANKL antibody.
Working concentration : 5 μg/ml

Anti-sRANKL antibody used in Western Blot (WB). GTX31300

GTX31300 WB Image

WB analysis of rat liver tissue lysate using GTX31300 sRANKL antibody.
Working concentration : (A) 0.25 and (B) 0.5 μg/ml

Package List Price ($)
$ 329