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OATP2 + OATP8 antibody [MDQ]

Anti-OATP2 + OATP8 antibody [MDQ] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX15442

Cat. No. GTX15442

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MDQ

Isotype

 IgG1

Application

 ICC/IF, IHC-P, IHC-Fr, IP

Reactivity

 Human, Mouse
Package
500 μl ($399)
See all OATP8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 1:20
IHC-P Assay dependent
IHC-Fr 1:20
IP Assay dependent
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to residues M(1) D Q N Q H L N K T A E A Q P S E N K K T R Y(23) C of human OATP2.

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_372564

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Background

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. [provided by RefSeq, Feb 2012]

Research Area

DATA IMAGES

Anti-OATP2 + OATP8 antibody [MDQ] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX15442

GTX15442 ICC/IF Image

ICC/IF analysis of HepG2 cells using GTX15442 OATP2 + OATP8 antibody [MDQ]. Cells were probed without (right) or with(left) an antibody.
Green : Primary antibody
Blue : Nuclei
Red : Actin
Fixation : formaldehyde
Dilution : 1:20 overnight at 4ºC

REFERENCE

Application Reference

Honsou Kim et al. Yonsei Med J 2021; 62 (7) : 622-630 Expression of Organic Anion Transporting Polypeptides in an H-Ras 12V Transgenic Mouse Model of Spontaneous Hepatocellular Carcinoma.
Application : IHC-P
Reactivity : Mouse
van de Steeg E et al. J Clin Invest 2012; 122 (2) : 519-28 Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.
Application : IHC-P
Reactivity : Human
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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399