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TNF alpha antibody

Orthogonal Overexpression
Anti-TNF alpha antibody used in Western Blot (WB). GTX110520
Anti-TNF alpha antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX110520
Anti-TNF alpha antibody used in Western Blot (WB). GTX110520
Anti-TNF alpha antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX110520
Anti-TNF alpha antibody used in Western Blot (WB). GTX110520
Anti-TNF alpha antibody used in Western Blot (WB). GTX110520
Anti-TNF alpha antibody used in Western Blot (WB). GTX110520
Anti-TNF alpha antibody used in Western Blot (WB). GTX110520
Anti-TNF alpha antibody used in Western Blot (WB). GTX110520
Anti-TNF alpha antibody used in Western Blot (WB). GTX110520
Anti-TNF alpha antibody used in Western Blot (WB). GTX110520
Anti-TNF alpha antibody used in Western Blot (WB). GTX110520
Anti-TNF alpha antibody used in Western Blot (WB). GTX110520
Anti-TNF alpha antibody used in IHC (Frozen sections) (IHC-Fr). GTX110520
Anti-TNF alpha antibody used in Western Blot (WB). GTX110520
Anti-TNF alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX110520
Anti-TNF alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX110520

Cat. No. GTX110520

Reference 81
1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IHC-Fr

Reactivity

 Human, Mouse, Rat, Bovine
Package
100 μl ($399),
25 μl ($169)
See all TNF alpha products
PRODUCT

Summary

TNF alpha antibody recognizes tumor necrosis factor alpha protein, a cytokine with a predicted molecular weight of 26 kDa. TNF alpha is mainly secreted by macrophages, but is also produced by various immune cells such as neutrophils, T helper cells, and NK cells. Dysregulation of TNF alpha expression is associated with various diseases including cancers and autoimmune disorders.

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
ICC/IF 1:100-1:1000
IHC-P 1:100-1:1000
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

Positive Control

NCI-H929 , C8D30 , PC-12 , Rat-2 , Raji , TNF-transfected 293T

Predict Reactivity

Cat, Dog, Pig, Chimpanzee, Rhesus Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.28 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length human TNF alpha Recombinant protein.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2885286

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

tumor necrosis factor , DIF , TNF-alpha , TNFA , TNFSF2 , TNLG1F

Cellular Localization

Cell membrane; Single-pass type II membrane protein , Tumor necrosis factor , soluble form: Secreted

Background

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-TNF alpha antibody used in Western Blot (WB). GTX110520

GTX110520 WB Image

Overexpression

Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with TNF alpha antibody (GTX110520) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-TNF alpha antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX110520

GTX110520 ICC/IF Image

TNF alpha antibody detects TNF alpha protein at membrane by immunofluorescent analysis.
Sample: jurkat cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: TNF alpha protein stained by TNF alpha antibody (GTX110520) diluted at 1:500.
Blue: Hoechst 33342 staining.
Anti-TNF alpha antibody used in Western Blot (WB). GTX110520

GTX110520 WB Image

TNF alpha antibody detects TNF alpha protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with TNF alpha antibody (GTX110520) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-TNF alpha antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX110520

GTX110520 ICC/IF Image

Orthogonal

TNF alpha antibody detects TNF alpha protein at cytoplasm by immunofluorescent analysis.
Sample: Raw264.7 cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: TNF alpha protein stained by TNF alpha antibody (GTX110520) diluted at 1:500.
Blue: Hoechst 33342 staining.
Anti-TNF alpha antibody used in Western Blot (WB). GTX110520

GTX110520 WB Image

TNF alpha antibody detects TNF alpha protein by western blot analysis. Whole cell extracts (30 μg) was separated by 12% SDS-PAGE, and the membrane was blotted with TNF alpha antibody (GTX110520) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-TNF alpha antibody used in Western Blot (WB). GTX110520

GTX110520 WB Image

Orthogonal

Untreated (–) and treated (+) THP-1 whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with TNF alpha antibody (GTX110520) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-TNF alpha antibody used in Western Blot (WB). GTX110520

GTX110520 WB Image

Orthogonal

Untreated (–) and treated (+) Raw264.7 whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with TNF alpha antibody (GTX110520) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-TNF alpha antibody used in Western Blot (WB). GTX110520

GTX110520 WB Image

Orthogonal

The data was published in the journal Front Neurol in 2017.PMID: 28713327

Anti-TNF alpha antibody used in Western Blot (WB). GTX110520

GTX110520 WB Image

Orthogonal

The data was published in the 2022 in Int J Mol Sci. PMID: 35628464

Anti-TNF alpha antibody used in Western Blot (WB). GTX110520

GTX110520 WB Image

Orthogonal

The data was published in the 2022 in Int J Mol Sci. PMID: 35628464

Anti-TNF alpha antibody used in Western Blot (WB). GTX110520

GTX110520 WB Image

Orthogonal

The data was published in the 2022 in Int J Mol Sci. PMID: 35628464

Anti-TNF alpha antibody used in Western Blot (WB). GTX110520

GTX110520 WB Image

Orthogonal

The data was published in the journal Int J Mol Sci in 2019. PMID: 30987270

Anti-TNF alpha antibody used in Western Blot (WB). GTX110520

GTX110520 WB Image

Orthogonal

The data was published in the journal Cardiovasc Diabetol in 2014. PMID: 24666525

Anti-TNF alpha antibody used in IHC (Frozen sections) (IHC-Fr). GTX110520

GTX110520 IHC-Fr Image

The data was published in the journal Nat Commun in 2019.PMID: 31757960

Anti-TNF alpha antibody used in Western Blot (WB). GTX110520

GTX110520 WB Image

The data was published in the journal Nat Commun in 2019.PMID: 31757960

Anti-TNF alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX110520

GTX110520 IHC-P Image

The data was published in the journal Front Pharmacol in 2017.PMID: 29184499

Anti-TNF alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX110520

GTX110520 IHC-P Image

The data was published in the 2022 in PLoS One. PMID: 35303036

REFERENCE

Application Reference

Zhao J et al. J Cell Mol Med 2024; 28 (7) : e18172 The relationship of ALPK1, hyaluronic acid and M1 macrophage polarization in the temporomandibular joint synovitis.
Tsurutani N et al. J Biol Chem 2024; 300 (3) : 105687 Intracellular trafficking of HIV-1 Gag via Syntaxin 6-positive compartments/vesicles: Involvement in tumor necrosis factor secretion.
Huang SC et al. J Tradit Complement Med 2023; 13 (5) : 511-520 Gastroprotective effects of Machilus zuihoensis Hayata bark against acidic ethanol-induced gastric ulcer in mice.
Gu X et al. Exp Ther Med 2023; 26 (3) : 413 1,25(OH)(2)D(3) ameliorates doxorubicin?induced cardiomyopathy by inhibiting the NLRP3 inflammasome and oxidative stress.
Torres-M?ndez JK et al. Nutrients 2023; 15 (14) Nicotinamide Prevents Diabetic Brain Inflammation via NAD+-Dependent Deacetylation Mechanisms.
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Submit a Reference

REVIEW

TNF alpha antibody Cat. No. GTX110520

Rating
( Average 4 based on 1 users reviews)
Application
Western Blot(WB)
( Average 4 based on 1 users reviews)
Anti-TNF alpha antibody used in Western Blot (WB). GTX110520
Date : Anonymous submitted on 22-Feb-2021
Score :
Application Tested : WB
Sample Species : Ms
Sample : colonic mucosa
Amount used : 25 μg
Blocking : 5% fat dry milk in TBST, 25°C, 1Hr
Primary Antibody : 1:1000, 4°C, 16Hr
Submit a Review
Application Reference
Zhao J et al. J Cell Mol Med 2024; 28 (7):e18172 The relationship of ALPK1, hyaluronic acid and M1 macrophage polarization in the temporomandibular joint synovitis.
Tsurutani N et al. J Biol Chem 2024; 300 (3):105687 Intracellular trafficking of HIV-1 Gag via Syntaxin 6-positive compartments/vesicles: Involvement in tumor necrosis factor secretion.
Huang SC et al. J Tradit Complement Med 2023; 13 (5):511-520 Gastroprotective effects of Machilus zuihoensis Hayata bark against acidic ethanol-induced gastric ulcer in mice.
Gu X et al. Exp Ther Med 2023; 26 (3):413 1,25(OH)(2)D(3) ameliorates doxorubicin?induced cardiomyopathy by inhibiting the NLRP3 inflammasome and oxidative stress.
Torres-M?ndez JK et al. Nutrients 2023; 15 (14) Nicotinamide Prevents Diabetic Brain Inflammation via NAD+-Dependent Deacetylation Mechanisms.
TC Chen et al. Ecotoxicol Environ Saf 2023; 263:115373 Assessing traffic-related air pollution-induced fiber-specific white matter degradation associated with motor performance declines in aged rats
Application : IHC-P
XIN GU et al. Exp Ther Med 2023; 26:413 1,25(OH)?D? ameliorates doxorubicin?induced cardiomyopathy by inhibiting the NLRP3 inflammasome and oxidative stress
Application : WB, IHC-P
Wu R et al. Cardiovasc Hematol Agents Med Chem 2023; 21 (3):232-239 Salvia miltiorrhiza Extract Prevents the Occurrence of Early Atherosclerosis in Apoe -/- Mice via TLR4/ NF-kB Pathway.
Ohnishi H et al. Int J Mol Sci 2023; 24 (10) Anti-Inflammatory Effects of Adiponectin Receptor Agonist AdipoRon against Intervertebral Disc Degeneration.
Zhang C et al. Curr Issues Mol Biol 2023; 45 (4):2703-2716 Long-Term Administration of LL-37 Can Induce Irreversible Rosacea-like Lesion.
Chu PC et al. Neurotherapeutics 2023; 20 (2):502-517 Pulsed Focused Ultrasound Reduces Hippocampal Volume Loss and Improves Behavioral Performance in the Kainic Acid Rat Model of Epilepsy.
Hsueh YH et al. J Orthop Translat 2023; 38:141-155 Therapeutic effect of induced pluripotent stem cell -derived extracellular vesicles in an in vitro and in vivo osteoarthritis model.
Chiou WC et al. Biomed Pharmacother 2023; 161:114481 Ovatodiolide inhibits SARS-CoV-2 replication and ameliorates pulmonary fibrosis through suppression of the TGF-β/TβRs signaling pathway.
Application : IHC-P
Reactivity : Mouse
Nakai A et al. Int Wound J 2023; 20 (4):1168-1182 Development of a method to identify persistent and blanchable redness by skin blotting in mice.
Application : IHC-P
Reactivity : Mouse
Locatelli M et al. Int J Mol Sci 2023; 24 (22) Endothelial Glycocalyx of Peritubular Capillaries in Experimental Diabetic Nephropathy: A Target of ACE Inhibitor-Induced Kidney Microvascular Protection.
Wen YH et al. Mater Today Bio 2022; 17:100482 Precise delivery of doxorubicin and imiquimod through pH-responsive tumor microenvironment-active targeting micelles for chemo- and immunotherapy.
Yamamoto T et al. J Dent Sci 2022; SARS-CoV-2 recombinant spike protein induces cell apoptosis in rat taste buds.
Mo S et al. Front Immunol 2022; 13:1050908 NF-κB-mediated anti-inflammatory effects of an organic light-emitting diode (OLED) device in lipopolysaccharide (LPS)-induced in vitro and in vivo inflammation models.
Application : IHC-P
Reactivity : Mouse
Kang Y et al. Drug Des Devel Ther 2022; 16:4127-4138 Thalidomide Attenuates Skin Lesions and Inflammation in Rosacea-Like Mice Induced by Long-Term Exposure of LL-37.
Yaqian Li et al. Int J Mol Sci 2022; 23 (10) Thalidomide Alleviates Pulmonary Fibrosis Induced by Silica in Mice by Inhibiting ER Stress and the TLR4-NF-κB Pathway.
Application : WB
Reactivity : Mouse
Adya Pramusita et al. Front Cell Dev Biol 2022; 10:816764 Salt-Sensitive Hypertension Induces Osteoclastogenesis and Bone Resorption via Upregulation of Angiotensin II Type 1 Receptor Expression in Osteoblasts.
Application : WB
Hossam G Tohamy et al. PLoS One 2022; 17 (3):e0265261 Protective potential of royal jelly against hydroxyurea -induced hepatic injury in rats via antioxidant, anti-inflammatory, and anti-apoptosis properties.
Reactivity : Rat
Juanjuan Duan et al. Nutrients 2022; 14 (3) Multifaceted Protective Effects of Hesperidin by Aromatic Hydrocarbon Receptor in Endothelial Cell Injury Induced by Benzo[a]Pyrene.
Application : ICC/IF
Reactivity : Human
Guo Z et al. Ecotoxicol Environ Saf 2022; 231:113210 Silica nanoparticles cause spermatogenesis dysfunction in mice via inducing cell cycle arrest and apoptosis.
Application : WB
Reactivity : Mouse
Mona A Hussain et al. Oxid Med Cell Longev 2021; 2021:8841726 Antioxidant and Anti-Inflammatory Effects of Crocin Ameliorate Doxorubicin-Induced Nephrotoxicity in Rats.
Reactivity : Rat
Fuyu Jin et al. J Inflamm Res 2021; 14:1647-1660 Ac-SDKP Attenuates Activation of Lung Macrophages and Bone Osteoclasts in Rats Exposed to Silica by Inhibition of TLR4 and RANKL Signaling Pathways.
Reactivity : Rat
Wei-Chung Chiou et al. Front Pharmacol 2021; 12:720018 Ugonin J Acts as a SARS-CoV-2 3C-like Protease Inhibitor and Exhibits Anti-inflammatory Properties.
Application : WB
Reactivity : Human
Na Mao et al. Int J Mol Sci 2021; 22 (18) Glycolytic Reprogramming in Silica-Induced Lung Macrophages and Silicosis Reversed by Ac-SDKP Treatment.
Application : WB
Reactivity : Rat
Navarro-Sempere A et al. Mediators Inflamm 2021; 2021:5891095 The Health Hazards of Volcanoes: First Evidence of Neuroinflammation in the Hippocampus of Mice Exposed to Active Volcanic Surroundings.
Su C.H. et al. Journal of Functional Foods 2021; 86 Betulin suppresses TNF-α and IL-1β production in osteoarthritis synovial fibroblasts by inhibiting the MEK/ERK/NF-κB pathway.
Application : WB
Reactivity : Human
Petrella C et al. Pharmacol Res 2021; 172:105795 Proneurogenic and neuroprotective effect of a multi strain probiotic mixture in a mouse model of acute inflammation: Involvement of the gut-brain axis.
Application : WB
Reactivity : Mouse
Muramatsu R et al. J Pharmacol Sci 2021; 147 (3):294-304 Guanabenz inhibits alveolar bone resorption in a rat model of periodontitis.
Reactivity : Rat
Law YY et al. Aging (Albany NY) 2021; 13 (13):17227-17236 miR-let-7c-5p and miR-149-5p inhibit proinflammatory cytokine production in osteoarthritis and rheumatoid arthritis synovial fibroblasts.
Application : WB
Reactivity : Human
Lam HYP et al. PLoS Negl Trop Dis 2021; 15 (6):e0009554 Ameliorative effects of Schisandrin B on Schistosoma mansoni-induced hepatic fibrosis in vivo.
Application : WB
Reactivity : Mouse
M?ndez-Lara KA et al. Antioxidants (Basel) 2020; 9 (11) Nicotinamide Prevents Apolipoprotein B-Containing Lipoprotein Oxidation, Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice.
Reactivity : Mouse
Liu T et al. J Cell Mol Med 2020; 24 (3):2189-2201 Circular RNA hsa_circRNA_002178 silencing retards breast cancer progression via microRNA-328-3p-mediated inhibition of COL1A1.
Zhou Y et al. Oncol Lett 2020; 20 (6):298 Anti-CD206 antibody-conjugated Fe3O4-based PLGA nanoparticles selectively promote tumor-associated macrophages to polarize to the pro-inflammatory subtype.
Application : WB
Reactivity : Mouse
Tsai MH et al. Cells 2020; 9 (8) Ischemic Stroke Risk Associated with Mitochondrial Haplogroup F in the Asian Population.
Application : WB
Reactivity : Human
Xia Y et al. Neuropsychopharmacology 2020; 45 (11):1896-1908 Modulating microglia activation prevents maternal immune activation induced schizophrenia-relevant behavior phenotypes via arginase 1 in the dentate gyrus.
Application : WB
Reactivity : Mouse
Chang JW et al. Cereb Cortex 2020; 30 (8):4597-4606 Ultrasound Stimulation Suppresses LPS-Induced Proinflammatory Responses by Regulating NF-κB and CREB Activation in Microglial Cells.
Application : WB
Reactivity : Rat
Li Q et al. J Ethnopharmacol 2020; 258:112896 Qiang-Gan formula extract improves non-alcoholic steatohepatitis via regulating bile acid metabolism and gut microbiota in mice.
Reactivity : Mouse
F Li et al. Sci Rep 2019; 9 (1):10078 XPNPEP2 is associated with lymph node metastasis in prostate cancer patients
Application : IHC-P
Reactivity : Mouse
Esposito E et al. Nat Commun 2019; 10 (1):5306 Brain-to-cervical lymph node signaling after stroke.
Application : WB
Reactivity : Rat
Thirugnanam K et al. J Am Heart Assoc 2019; 8 (22):e012792 Cardiomyocyte-Specific Snrk Prevents Inflammation in the Heart.
Application : WB
Reactivity : Mouse
Huang TW et al. Neuropeptides 2019; 78:101964 Neuropeptide Y increases differentiation of human olfactory receptor neurons through the Y1 receptor.
Reactivity : Human
Hsiao HT et al. J Biomed Sci 2019; 26 (1):74 The analgesic effect of propofol associated with the inhibition of hypoxia inducible factor and inflammasome in complex regional pain syndrome.
Application : WB
Reactivity : Mouse
Liu J et al. JBMR Plus 2019; 3 (5):e10122 Identification of Genes Differentially Expressed in Simvastatin-Induced Alveolar Bone Formation.
Wei L et al. Brain Res 2019;:146423 Complement C3 participates in the function and mechanism of traumatic brain injury at simulated high altitude.
Reactivity : Rat
Wang Q et al. J Cell Biochem 2019; The comparison of the effects of local cooling and heating on apoptosis and pyroptosis of early-stage pressure ulcers in rats.
Huang S et al. Med Devices (Auckl) 2019; 12:399-410 In vitro safety and performance evaluation of a seawater solution enriched with copper, hyaluronic acid, and eucalyptus for nasal lavage.
Liu J et al. Mol Immunol 2019; 116:56-62 Bisperoxovanadium induces M2-type macrophages and promotes functional recovery after spinal cord injury.
Huang TW et al. Acta Biomater 2019; (Epub) Regulation of chitosan-mediated differentiation of human olfactory receptor neurons by insulin-like growth factor binding protein-2.
Application : WB, ICC/IF
Reactivity : Human
Wang HS et al. J Dent Res 2019;:22034519869580 Odontoblastic Exosomes Attenuate Apoptosis in Neighboring Cells.
Application : WB
Reactivity : Human
Cao W et al. Clin Sci (Lond) 2019; (Epub) Adipocytes initiates an adipose-cerebral-peripheral sympathetic reflex to induce insulin resistance during high fat feeding.
Application : WB
Liu YY et al. Mol Pain 2019; 15:1744806919855204 Rib soft fixation produces better analgesic effects and is associated with cytokine changes within the spinal cord in a rat rib fracture model.
Application : WB
Reactivity : Rat
Chen CC et al. Transl Res 2019; (Epub) Pigment epithelium-derived factor inhibits adipogenesis in 3T3-L1 adipocytes and protects against high-fat diet-induced obesity and metabolic disorders in mice.
Application : WB
Reactivity : Mouse
Zhu M et al. Pathol Res Pract 2019;:152388 Inhibitory effects of bortezomib in a subcutaneous tumor model of H22 mouse hepatocarcinoma cells.
Reactivity : Mouse
El-Sayed RM et al. Can J Physiol Pharmacol 2019; 97 (5):359-369
Reactivity : Mouse
Lee YC et al. Int J Mol Sci 2019; 20 (7) Essential Role of Visfatin in Lipopolysaccharide and Colon Ascendens Stent Peritonitis-Induced Acute Lung Injury.
Application : WB
Reactivity : Human
Ji Y et al. Front Pharmacol 2019; 10:142 Vildagliptin Reduces Stenosis of Injured Carotid Artery in Diabetic Mouse Through Inhibiting Vascular Smooth Muscle Cell Proliferation via ER Stress/NF-κB Pathway.
Application : WB
Reactivity : Mouse
Du Y et al. Am J Transl Res 2018; 10 (12):4235-4246 Muscone improves cardiac function in mice after myocardial infarction by alleviating cardiac macrophage-mediated chronic inflammation through inhibition of NF-庥B and NLRP3 inflammasome.
Fujimura M et al. Toxicol Sci 2018; (Epub) Fasudil, a ROCK inhibitor, recovers methylmercury-induced axonal degeneration by changing microglial phenotype in rats.
Application : WB
Reactivity : Rat
Chen CM et al. J Renin Angiotensin Aldosterone Syst 2018; 19 (3):1.47E+15 Hyperglycemia activates the renin-angiotensin system and induces epithelial-mesenchymal transition in streptozotocin-induced diabetic kidneys.
Zhou Y et al. Cancer Med 2018; (Epub) Iron overloaded polarizes macrophage to proinflammation phenotype through ROS/acetyl-p53 pathway.
Application : WB
Reactivity : Mouse
Liu B et al. Stem Cell Res Ther 2018; 9 (1):7 Human umbilical cord mesenchymal stem cell conditioned medium attenuates renal fibrosis by reducing inflammation and epithelial-to-mesenchymal transition via the TLR4/NF-κB signaling pathway in vivo and in vitro.
Application : WB
Reactivity : Rat
Gao W et al. Front Neurol 2017; 8:281 IL-2/Anti-IL-2 Complex Attenuates Inflammation and BBB Disruption in Mice Subjected to Traumatic Brain Injury.
Application : WB
Reactivity : Mouse
Su K et al. Mediators Inflamm 2017; 2017:3701385 FTY720 Attenuates Angiotensin II-Induced Podocyte Damage via Inhibiting Inflammatory Cytokines.
Li ST et al. Acta Biomater 2017; (Epub) Poly (ethylene-co-vinyl alcohol) is a suitable substrate for human olfactory neuroepithelial cell differentiation in vitro through a defined regulatory pathway.
Application : WB, ICC/IF
Reactivity : Human
Chiang MH et al. Front Pharmacol 2017; 8:819 Aliskiren Improves Ischemia- and Oxygen Glucose Deprivation-Induced Cardiac Injury through Activation of Autophagy and AMP-Activated Protein Kinase.
Reactivity : Mouse
Yu T et al. Am J Transl Res 2017; 9 (10):4682-4693 topical * accelerates cutaneous wound healing in *-resistant diabetic rats.
Reactivity : Rat
Chen H et al. Am J Respir Cell Mol Biol 2017; (Epub) Maternal E-cigarette Exposure in Mice Alters DNA Methylation and Lung Cytokine Expression in Offspring.
Application : WB
Reactivity : Mouse
Li ST et al. Am J Rhinol Allergy 2017; 31 (5):289-292 Promotion of olfactory receptor neuron differentiation of olfactory neuroepithelial cells by using chitosan solution.
Chen YC et al. J Formos Med Assoc 2017; Anti-inflammation performance of curcumin-loaded mesoporous calcium silicate cement.
Application : WB
Reactivity : Human
Kuo CY et al. Cancer Res 2017; (Epub) VHL inactivation in precancerous kidney cells induces an inflammatory response via ER stress-activated IRE1α signaling.
Application : WB
Reactivity : Human
Huang YC et al. Toxicol Appl Pharmacol 2017; 329:128-139 galangin ameliorates *-induced nephrotoxicity by attenuating oxidative stress, inflammation and cell death in mice through inhibition of erk and nf-kappab signaling.
Application : WB
Reactivity : Mouse
Liu Q et al. Exp Mol Med 2017; 49 (4):e319 Cyclophosphamide-induced HCN1 channel upregulation in interstitial Cajal-like cells leads to bladder hyperactivity in mice.
Application : WB
Reactivity : Human
Liang J et al. Medicine (Baltimore) 2016; 95 (52):e5763 The expression of thymosin β4 in chronic hepatitis B combined nonalcoholic fatty liver disease.
Reactivity : Human
Chou HC et al. Clin Exp Pharmacol Physiol 2016; (Epub) Human mesenchymal stem cells attenuate pulmonary hypertension induced by prenatal lipopolysaccharide treatment in rats.
Reactivity : Rat
Fang S et al. Neuromolecular Med 2016; Vorinostat Modulates the Imbalance of T Cell Subsets, Suppresses Macrophage Activity, and Ameliorates Experimental Autoimmune Uveoretinitis.
Application : WB
Reactivity : Mouse
Chen WL et al. PLoS One 2015; 10 (9):e0137979 Mycobacterium tuberculosis Upregulates TNF-α Expression via TLR2/ERK Signaling and Induces MMP-1 and MMP-9 Production in Human Pleural Mesothelial Cells.
Application : WB
Reactivity : Human
Lee AS et al. Cardiovasc Diabetol 2014; 13:64 Gender disparity in LDL-induced cardiovascular damage and the protective role of estrogens against electronegative LDL.
Application : WB
Reactivity : Mouse
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