Rat Brain Tissue Lysate(GTX27942)
Liquid
PBS
0.02% Sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Human
TRESK antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRESK.The immunogen is located within amino acids 210 - 260 of TRESK.
Purified by antigen-affinity chromatography
Unconjugated
potassium two pore domain channel subfamily K member 18 , K2p18.1 , MGR13 , TRESK , TRESK-2 , TRESK2 , TRIK
Cell membrane
TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.
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GTX85212 IHC-P Image
IHC-P analysis of rat brain tissue using GTX85212 TRESK antibody. Working concentration : 5 μg/ml
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GTX85212 IHC-P Image
IHC-P analysis of rat brain tissue using GTX85212 TRESK antibody. Working concentration : 20 μg/ml
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GTX85212 WB Image
WB analysis of rat brain tissue lysate using GTX85212 TRESK antibody. Working concentration : (A) 1 and (B) 2 μg/ml
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