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5-HT2B receptor antibody

Anti-5-HT2B receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX32984
Anti-5-HT2B receptor antibody used in Western Blot (WB). GTX32984
Anti-5-HT2B receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX32984
Anti-5-HT2B receptor antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32984

Cat. No. GTX32984

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all 5-HT2B receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:10 - 1:100
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 382-481 of human HTR2B (NP_000858.3).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

5-hydroxytryptamine receptor 2B , 5-HT(2B) , 5-HT-2B , 5-HT2B

Cellular Localization

Cell membrane

Background

This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]

Database

Research Area

DATA IMAGES

Anti-5-HT2B receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX32984

GTX32984 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX32984 5-HT2B receptor antibody.
Dilution : 1:100

Anti-5-HT2B receptor antibody used in Western Blot (WB). GTX32984

GTX32984 WB Image

WB analysis of various sample lysates using GTX32984 5-HT2B receptor antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-5-HT2B receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX32984

GTX32984 IHC-P Image

IHC-P analysis of rat brain tissue using GTX32984 5-HT2B receptor antibody.
Dilution : 1:100

Anti-5-HT2B receptor antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32984

GTX32984 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX32984 5-HT2B receptor antibody.
Blue : DAPI

REFERENCE

Application Reference

Owaki T et al. Dis Model Mech 2022; 15 (7) Involvement of the liver-gut peripheral neural axis in nonalcoholic fatty liver disease pathologies via hepatic HTR2A.
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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399