GeneTex
United States (US)

5-HT2B receptor antibody

GTX32984_20180530_WB_18121410_287.jpg
GTX32984_20180530_IHC-P_18121410_397.jpg
GTX32984_20180530_IHC-P_1_18121410_815.jpg

Cat No. GTX32984

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

54 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 382-481 of human HTR2B (NP_000858.3).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

5-Hydroxytryptamine Receptor 2B,5-Ht(2B),5-Ht-2B,5-Ht2B,Htr2B

Background

This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. [provided by RefSeq, Oct 2011]

Database

Research Area

DATA IMAGES
GTX32984_20180530_WB_18121410_287.jpg

GTX32984 WB Image

WB analysis of various samples using GTX32984 5-HT2B receptor antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX32984_20180530_IHC-P_18121410_397.jpg

GTX32984 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX32984 5-HT2B receptor antibody.
Dilution : 1:100

GTX32984_20180530_IHC-P_1_18121410_815.jpg

GTX32984 IHC-P Image

IHC-P analysis of rat brain tissue using GTX32984 5-HT2B receptor antibody.
Dilution : 1:100

Package List Price ($)
$ 329