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5-HT2B receptor antibody

Anti-5-HT2B receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX70503
Anti-5-HT2B receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX70503
Anti-5-HT2B receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX70503
Anti-5-HT2B receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX70503
Anti-5-HT2B receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX70503

Cat No. GTX70503

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Rat
Package
25 μg ($269)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P 3 μg/ml
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

Predict Reactivity

Rabbit, Bovine, Dog, Monkey, Bat, Chimpanzee, Gorilla, Horse, Marmoset, Orangutan, Panda(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 20 amino acid peptide from N-terminal extracellular domain of human 5HT2B Receptor.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

HTR2B , Serotonin receptor 2B , SR-2B , 5-hydroxytryptamine receptor 2B , 5HT(2B) , 5HT2B , 5hydroxytryptamine receptor 2B , 5HT2B Receptor , 5-HT2B receptor

Cellular Localization

Cell membrane,Cell junction, synapse, synaptosome

Background

This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]

Database

Research Area

DATA IMAGES

Anti-5-HT2B receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX70503

GTX70503 IHC-P Image

IHC-P analysis of human lung, small cell carcinoma tissue using GTX70503 5-HT2B receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-5-HT2B receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX70503

GTX70503 IHC-P Image

IHC-P analysis of human brain, glioblastoma tissue using GTX70503 5-HT2B receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-5-HT2B receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX70503

GTX70503 IHC-P Image

IHC-P analysis of brain, amygdala neurons tissue using GTX70503 5-HT2B receptor antibody.

Anti-5-HT2B receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX70503

GTX70503 IHC-P Image

IHC-P analysis of human brain, neurons and glia tissue using GTX70503 5-HT2B receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-5-HT2B receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX70503

GTX70503 IHC-P Image

IHC-P analysis of brain, substantia nigra tissue using GTX70503 5-HT2B receptor antibody.

REFERENCE

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf