*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Rabbit, Bovine, Dog, Monkey, Bat, Chimpanzee, Gorilla, Horse, Marmoset, Orangutan, Panda(>80% identity)
PBS, 0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Synthetic 20 amino acid peptide from N-terminal extracellular domain of human 5HT2B Receptor.
Purified by affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
HTR2B , Serotonin receptor 2B , SR-2B , 5-hydroxytryptamine receptor 2B , 5HT(2B) , 5HT2B , 5hydroxytryptamine receptor 2B , 5HT2B Receptor , 5-HT2B receptor
Cell membrane,Cell junction, synapse, synaptosome
This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]