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5-HT2C receptor antibody

Anti-5-HT2C receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX03808
Anti-5-HT2C receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX03808

Cat. No. GTX03808

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IP, ELISA

Reactivity

 Human, Mouse, Rat, Baboon
Package
100 μg ($409)
See all 5-HT2C receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500
IHC-P 1:50-1:100
IP 1:200
ELISA 1:50,000
Not tested in other applications.

Calculated MW

52 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tris/Glycine pH 7.4-7.9, 30% glycerol, BSA

Preservative

0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide taken within amino acid region 400-458 on human 5-hydroxytryptamine receptor 2C.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

5-hydroxytryptamine receptor 2C , 5-HT1C , 5-HT2C , 5-HTR2C , 5HTR2C , HTR1C

Cellular Localization

Cell membrane

Background

This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants. [provided by RefSeq, Jan 2015]

Database

Research Area

DATA IMAGES

Anti-5-HT2C receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX03808

GTX03808 IHC-P Image

WB analysis of human fibroepithelial polyp tissue using GTX03808 5-HT2C receptor antibody.
Dilution : 1:50

Anti-5-HT2C receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX03808

GTX03808 IHC-P Image

WB analysis of baboon brain tissue using GTX03808 5-HT2C receptor antibody.
Dilution : 1:50

REFERENCE

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REVIEW

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Package List Price ($)
$ 409