APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 5.6 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Monkey, Chimpanzee, Elephant, Gibbon, Gorilla, Horse, Marmoset, Orangutan, Panda(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human 5HT2C Receptor.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_424887
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
HTR1C , HTR2C , Serotonin receptor 2C , SR-2C , 5-hydroxytryptamine receptor 2C , 5HT1C , 5HT2C , 5HTR2C , 5hydroxytryptamine receptor 2C , 5HT2C Receptor , 5-HT2C receptor
Cellular Localization
Cell membrane
Background
This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants. [provided by RefSeq, Jan 2015]
Database
Research Area
DATA IMAGES
|
GTX77939 IHC-P Image
IHC-P analysis of human uterus, glandular cells tissue using GTX77939 5-HT2C receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval
|
REFERENCE
There are currently no references for 5-HT2C receptor antibody (GTX77939). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for 5-HT2C receptor antibody (GTX77939). Be the first to share your experience with this product.
