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5-HT3A receptor antibody

Anti-5-HT3A receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX54151
Anti-5-HT3A receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX54151
Anti-5-HT3A receptor antibody used in Western Blot (WB). GTX54151

Cat. No. GTX54151

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all 5-HT3A receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

55 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 24-241 of human HTR3A (NP_000860.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

5-hydroxytryptamine receptor 3A , 5-HT-3 , 5-HT3A , 5-HT3R , 5HT3R , HTR3

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-5-HT3A receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX54151

GTX54151 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX54151 5-HT3A receptor antibody.
Dilution : 1:100

Anti-5-HT3A receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX54151

GTX54151 IHC-P Image

IHC-P analysis of rat brain tissue using GTX54151 5-HT3A receptor antibody.
Dilution : 1:100

Anti-5-HT3A receptor antibody used in Western Blot (WB). GTX54151

GTX54151 WB Image

WB analysis of various sample lysates using GTX54151 5-HT3A receptor antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399