GeneTex
United States (US)

5-HT3B receptor antibody, Internal (near C-terminus)

GTX88391_2380_WB_18122102_490.jpg

Cat No. GTX88391

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-3μg/ml
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88391-PEP).
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Concentration

0.50mg/ml

Antigen Species

Human

Immunogen

Peptide with sequence C-SNYLQTQDQTDQQE, from the internal region (near C-terminus) of the protein sequence according to NP_006019.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

HTR3B Antibody , 5HT3B Antibody

Cellular Localization

Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.

Background

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor. [provided by RefSeq, Aug 2011]
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Database

Research Area

DATA IMAGES
GTX88391_2380_WB_18122102_490.jpg

GTX88391 WB Image

WB analysis of human cerebral cortex lysate using GTX88391 5-HT3B receptor antibody, Internal (near C-terminus).
Dilution : 1µg/ml
Loading : 35µg protein in RIPA buffer