APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 - 2 μg/mL |
| 5 μg/mL |
| 5 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
HEK293 Cell Slide(GTX25524) , HEK293 Cell Lysate(GTX27902) , Human Spleen Tissue Slide
Product Note
ABCA7 antibody is predicted to not cross-react with other ABC1 subfamily proteins.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
ABCA7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human ABCA7.The immunogen is located within amino acids 130 - 180 of ABCA7.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
ATP binding cassette subfamily A member 7 , ABCA-SSN , ABCX , AD9
Cellular Localization
Cell membrane,Golgi apparatus membrane,Cytoplasm,Endoplasmic reticulum
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX31856 IHC-P Image
IHC-P analysis of human spleen tissue using GTX31856 ABCA7 antibody.
Working concentration : 20 μg/ml
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GTX31856 ICC/IF Image
ICC/IF analysis of 293 cells using GTX31856 ABCA7 antibody.
Working concentration : 5 μg/ml
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GTX31856 IHC-P Image
IHC-P analysis of human spleen tissue using GTX31856 ABCA7 antibody.
Working concentration : 5 μg/ml
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GTX31856 ICC/IF Image
ICC/IF analysis of 293 cells using GTX31856 ABCA7 antibody.
Working concentration : 20 μg/ml
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GTX31856 WB Image
WB analysis of 293 cell lysate using GTX31856 ABCA7 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml
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REFERENCE
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REVIEW
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