GeneTex
United States (US)

ABCC11 antibody, Internal

GTX88673_2183_WB_18121411_669.jpg
GTX88673_876_IHC-P_18121411_656.jpg

Cat No. GTX88673

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5-1.5μg/ml
IHC-P 3.75μg/ml
Not tested in other applications.

Calculated MW

154 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88673-PEP).

Specificity/Sensitivity

This antibody is expected to recognize both reported isoforms (NP_115972.2; NP_660187.1).
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-KVVEFDRPEVLRK, from the internal region (near C Terminus) of the protein sequence according to NP_115972.2; NP_660187.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Atp Binding Cassette Subfamily C Member 11,Ewwd,Mrp8,Ww,Abcc11

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX88673_2183_WB_18121411_669.jpg

GTX88673 WB Image

WB analysis of human breast lysate using GTX88673 ABCC11 antibody, Internal.
Dilution : 0.5µg/ml
Loading : 35µg protein in RIPA buffer

GTX88673_876_IHC-P_18121411_656.jpg

GTX88673 IHC-P Image

IHC-P analysis of human breast using GTX88673 ABCC11 antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.75µg/ml

Package List Price ($)
$ 329