GeneTex
United States (US)

ABCG1 antibody

Orthogonal
GTX30598_326_IHC-P_18121410_969.jpg
GTX30598_1417_WB_18121410_271.jpg
GTX30598_1419_WB_18121410_828.jpg

Cat No. GTX30598

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P, in vitro
Reactivity Human, Mouse, Rat, Rabbit, Hamster, Monkey
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500
ICC/IF Assay dependent
IHC-P 1:100 - 1:400
in vitro Assay dependent
Not tested in other applications.

Calculated MW

76 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS, 0.02% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide made to an internal region of human ABCG1 (between residues 300-400). [UniProt# P45844]

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Atp Binding Cassette Subfamily G Member 1,Abc8,White1,Abcg1

Cellular Localization

Endoplasmic reticulum membrane,Golgi apparatus membrane

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX30598_326_IHC-P_18121410_969.jpg

GTX30598 IHC-P Image

IHC-P analysis of human lung tissue using GTX30598 ABCG1 antibody.

GTX30598_1417_WB_18121410_271.jpg

GTX30598 WB Image

WB analysis of mouse peritoneal macrophages using GTX30598 ABCG1 antibody.
Lane 1 : untreated mouse peritoneal macrophages (positive control)
Lane 2 : 22-(R)-hydrocholesterol treated macrophages
Lane 3 : T0901713 treated macrophages
Lane 4 : T0901713 treated macrophages

GTX30598_1419_WB_18121410_828.jpg

GTX30598 WB Image

Orthogonal

WB analysis of RAW264.7 (A), and RAW264.7 treated with 10uM T09 18 hr (B) cell lysate using GTX30598 ABCG1 antibody.
Dilution : 2 μg/ml

REFERENCE
Package List Price ($)
$ 349
Current in productions