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ABCG2 antibody [2J39]

Anti-ABCG2 antibody [2J39] used in IHC (Paraffin sections) (IHC-P). GTX52498

Cat. No. GTX52498

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 2J39

Isotype

 IgG2

Application

 ICC/IF, IHC-P, FACS

Reactivity

 Human
Package
100 μg ($399)
See all ABCG2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 1:100 - 1:1000
IHC-P Assay dependent
FACS 1:100 - 1:1000
Not tested in other applications.

Calculated MW

72 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant rHABCG2 protein

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ABC15 , ABCG2 , ABCP , ATP binding cassette subfamily G member 2 (Junior blood group) , BCRP , BCRP1 , BMDP , CD338 , CDw338 , EST157481 , GOUT1 , MRX , MXR , MXR1 , UAQTL1

Cellular Localization

Cell membrane,Mitochondrion membrane

Background

The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Database

Research Area

DATA IMAGES

Anti-ABCG2 antibody [2J39] used in IHC (Paraffin sections) (IHC-P). GTX52498

GTX52498 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52498 ABCG2 antibody [2J39].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399