GeneTex
United States (US)

ABCG2 antibody [BXP-21]

Cat No. GTX23380

Host Mouse
Clonality Monoclonal
Clone Name BXP-21
Isotype IgG2a
Application WB, ICC/IF, IHC-P, IHC-Fr, FACS
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF 1:20-1:50
IHC-P Assay dependent
IHC-Fr 1:20
FACS Assay dependent
Not tested in other applications.

Calculated MW

72 kDa. ( Note )

Specificity/Sensitivity

Reacts with an internal epitope of BCRP. Does not cross-react with the human MDR1, MRP1, MRP2 gene products.
PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant (Serum free medium) with 0.7% bovine Serum albumin, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

~250μg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

fusion protein containing human BCRP (amino acids 271-396) and maltose-binding protein.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

BCRP, BMDP, BCRP1, MXR, ABC15, 9429, ABCP, Q9UNQ0, ABCG2, 603756, EST157481, MGC102821, MXR1, MRX, CD338, CDw338

Background

Breast Cancer Resistance Protein (BCRP) is a 70 kDa ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone.

Database

Research Area

REFERENCE
Application Reference
Package List Price ($)
$ 319