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ABCG2 antibody [BXP-21]

Cat No. GTX23380

Host

Mouse

Clonality

Monoclonal

Clone Name

BXP-21

Isotype

IgG2a

Application

WB, ICC/IF, IHC-P, IHC-Fr, FACS

Reactivity

Human
Package
250 μl ($359)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF 1:20-1:50
IHC-P Assay dependent
IHC-Fr 1:20
FACS Assay dependent
Not tested in other applications.

Calculated MW

72 kDa. ( Note )

Product Note

Reacts with an internal epitope of BCRP. Does not cross-react with the human MDR1, MRP1, MRP2 gene products.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant (Serum free medium) with 0.7% bovine Serum albumin, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

fusion protein containing human BCRP (amino acids 271-396) and maltose-binding protein.

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_379784

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ATP binding cassette subfamily G member 2 (Junior blood group) , ABC15 , ABCP , BCRP , BCRP1 , BMDP , CD338 , CDw338 , EST157481 , GOUT1 , MRX , MXR , MXR-1 , MXR1 , UAQTL1

Cellular Localization

Cell membrane

Background

Breast Cancer Resistance Protein (BCRP) is a 70 kDa ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone.

Database

Research Area

REFERENCE

REVIEW

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Application Reference
SDS
Sodium Azide.pdf