*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Reacts with an internal epitope of BCRP. Does not cross-react with the human MDR1, MRP1, MRP2 gene products.
Tissue culture supernatant (Serum free medium) with 0.7% bovine Serum albumin, 0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
fusion protein containing human BCRP (amino acids 271-396) and maltose-binding protein.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ATP binding cassette subfamily G member 2 (Junior blood group) , ABC15 , ABCP , BCRP , BCRP1 , BMDP , CD338 , CDw338 , EST157481 , GOUT1 , MRX , MXR , MXR-1 , MXR1 , UAQTL1
Breast Cancer Resistance Protein (BCRP) is a 70 kDa ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone.