*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
A549 , H1299 , HCT116 , NIH-3T3
Rat, Sheep, Bovine, Dog, Pig, Rhesus Monkey(>80% identity)
1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1mg/ml(Please refer to the vial label for the specific concentration.)
Recombinant protein encompassing a sequence within the center region of human ABCG2. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ABC15 antibody, ABCP antibody, BCRP antibody, BCRP1 antibody, BMDP antibody, CD338 antibody, CDw338 antibody, EST157481 antibody, MGC102821 antibody, MRX antibody, MXR antibody, MXR1 antibody, ABCG2 antibody, ATP-binding cassette sub-family G member 2 antibody, mitoxantrone resistance-associated protein antibody, breast cancer resistance protein antibody, ATP-binding cassette transporter G2 antibody, placenta-specific ATP-binding cassette transporter antibody, multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) member 2 antibody, placenta specific MDR protein antibody, mitoxantrone resistance protein antibody, ABC transporter antibody, ATP-binding cassette, sub-family G (WHITE), member 2 antibody
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. [provided by RefSeq]