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ABCG8 antibody

Anti-ABCG8 antibody used in Western Blot (WB). GTX30466

Cat No. GTX30466

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB

Reactivity

Human
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

Product Note

We do not recommend use of this product for Mouse.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide from the N-terminal region of human ABCG8 protein. [UniProt# Q9H221]

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_385628

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ATP binding cassette subfamily G member 8 , GBD4 , STSL

Cellular Localization

Cell membrane,Apical cell membrane

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-ABCG8 antibody used in Western Blot (WB). GTX30466

GTX30466 WB Image

WB analysis of mouse liver microsomes from abcg5/abcg8 knockout mice, wildtype human abcg5/abcg8, and transgenic human abcg5/abcg8 using GTX30466 ABCG8 antibody.

REFERENCE

REVIEW

ABCG8 antibody Cat No. GTX30466

Rating ( Average 5 based on 1 users reviews)
Application
Western Blot(WB) ( Average 5 based on 1 users reviews)
Date : Anonymous submitted on 10-Aug-2021
Score :
Application Tested : WB
Sample Species : Hu
Figure Note : The data was peer reviewed and published in the journal PLoS One in 2016.PMID: 27023132
SDS
PBS.pdf
Sodium Azide.pdf