ACCN1 antibody

Cat. No. GTX54802

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF, IP, IHC
Reactivity	Human, Mouse, Rat
Package	50 μl ($639)

See all ACCN1 products

Datasheet
Document

View product citations for antibody GTX54802 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	Assay dependent
ICC/IF	Assay dependent
IP	Assay dependent
IHC	Assay dependent

Not tested in other applications.

Calculated MW

58 kDa. ( Note )

Product Note

The antibody is specific for ASIC2a and will not recognize ASIC2b.

PROPERTIES

Form

Liquid

Buffer

PBS pH7.4, 1% BSA, 5% Sucrose

Preservative

0.025% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.3 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide DLKESPSEGSLQPSSIQC, corresponding to amino acid residues 2-18 (Intracellular, N-terminus) of human ASIC2a (Accession Q16515).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

acid sensing ion channel subunit 2 , ACCN , ACCN1 , ASIC2a , BNC1 , BNaC1 , MDEG , hBNaC1

Cellular Localization

Cell membrane

Background

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Feb 2012]

Database

Gene ID: 40 ASIC2
UniProt: Q16515 ASIC2

Research Area

DATA IMAGES

GTX54802 WB Image

WB analysis of rat brain membrane lysate using GTX54802 ACCN1 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf

Package

List Price ($)

50 μl

$ 639

Qty