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ACE antibody [12J16]

Anti-ACE antibody [12J16] used in Western Blot (WB). GTX52523

Cat. No. GTX52523

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 12J16

Isotype

 IgG1

Application

 WB

Reactivity

 Human
Package
100 μg ($399)
See all ACE products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

150 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human ACE (EC domain)

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ACE , ACE1 , CD143 , DCP , DCP1 , angiotensin I converting enzyme

Cellular Localization

Secreted,Cell membrane,Cytoplasm

Background

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES

Anti-ACE antibody [12J16] used in Western Blot (WB). GTX52523

GTX52523 WB Image

WB analysis of human lung tissue using GTX52523 ACE antibody [12J16].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399