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ACE antibody [2E2]

Cat No. GTX11734

Host Mouse
Clonality Monoclonal
Clone Name 2E2
Isotype IgG1
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat, Rabbit, Bovine, Cat, Dog, Guinea pig, Pig, Monkey
Package
500 μl ($319)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1/50-1/100
IHC-P 1/20
ELISA Assay dependent

Note :

IHC-P
This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.

Not tested in other applications.

Calculated MW

150 kDa. ( Note )

Specificity/Sensitivity

This antibody recognizes denatured ACE.
PROPERTIES

Form

Liquid

Buffer

Tissue Culture Supernatant with 0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Denatured Human kidney CD143 (ACE).

Purification

Tissue Culture Supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Angiotensin I Converting Enzyme , Ace1 , Cd143 , Dcp , Dcp1 , Ace

Background

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]

Database

Research Area

REFERENCE
REVIEW
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Package List Price ($)
$ 319