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ACE antibody

Anti-ACE antibody used in IHC (Paraffin sections) (IHC-P). GTX54938
Anti-ACE antibody used in Western Blot (WB). GTX54938

Cat No. GTX54938

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
Package
100 μl ($319)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

150 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.42% Potassium phosphate, 0.87% Sodium chloride pH 7.3, 30% glycerol, 0.01% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of ACE. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

angiotensin I converting enzyme , ACE1 , CD143 , DCP , DCP1

Cellular Localization

Cytoplasm

Background

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES
Anti-ACE antibody used in IHC (Paraffin sections) (IHC-P). GTX54938

GTX54938 IHC-P Image

IHC-P analysis of formalin fixed human breast cancer tissue section using GTX54938 ACE antibody.
Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)

Anti-ACE antibody used in Western Blot (WB). GTX54938

GTX54938 WB Image

WB analysis of HeLa (A), mouse kidney (B), rat liver (C), PC12 (D) whole cell lysates using GTX54938 ACE antibody.

REFERENCE
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REVIEW
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Package List Price ($)
$ 319