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ACVRL1 antibody [8G33]

Anti-ACVRL1 antibody [8G33] used in IHC (Paraffin sections) (IHC-P). GTX52468

Cat. No. GTX52468

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 8G33

Isotype

 IgG2

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all ACVRL1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:200 - 1:800
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

56 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human TGF RI (ALK1) extra-cellular domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ACVRL1 , ACVRLK1 , ALK1 , HHT , HHT2 , ORW2 , SKR3 , TSRI , activin A receptor like type 1 , Activin A receptor like type 1

Cellular Localization

Membrane

Background

This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 94 ACVRL1
  • UniProt: P37023 ACVRL1

Research Area

DATA IMAGES

Anti-ACVRL1 antibody [8G33] used in IHC (Paraffin sections) (IHC-P). GTX52468

GTX52468 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52468 ACVRL1 antibody [8G33].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399