GeneTex
United States (US)

ACVRL1 antibody [C3], C-term

GTX100035_39408_WB_M_19011505_770.jpg
GTX100035_39408_IHC_19011505_590.jpg
GTX100035_WB_19011506_333.jpg

Cat No. GTX100035

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000-1:10000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

56 kDa. ( Note )

Positive Control

293T , 293T mem , HepG2 , HepG2 mem , BCL-1
PROPERTIES

Form

Liquid

Buffer

1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ACVRL1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ACVRLK1 antibody, ALK-1 antibody, ALK1 antibody, HHT antibody, HHT2 antibody, ORW2 antibody, SKR3 antibody, TSR-I antibody, ACVRL1 antibody, TGF-B superfamily receptor type I antibody, serine/threonine-protein kinase receptor R3 antibody, activin receptor-like kinase 1 antibody, "activin A receptor, type II-like kinase 1 antibody", activin A receptor type II-like 1 antibody

Cellular Localization

Membrane

Background

This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX100035_39408_WB_M_19011505_770.jpg

GTX100035 WB Image

Sample (30 ug of whole cell lysate)
A: BCL-1
10% SDS PAGE
GTX100035 diluted at 1:1000

GTX100035_39408_IHC_19011505_590.jpg

GTX100035 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human heart, using Activin A Receptor Type II-like 1(GTX100035) antibody(20 μg/ml).
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX100035_WB_19011506_333.jpg

GTX100035 WB Image

Sample (20 ug of whole cell lysate)
A: Hep G2 (GTX27900) membrane extract
7.5% SDS PAGE
GTX100035 diluted at 1:5000

REFERENCE
SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Document
Unmodified.pdf