ACVRL1 antibody [C3], C-term

Name: ACVRL1 antibody [C3], C-term
Brand: GeneTex
SKU: GTX100035
Price: 399.00 USD
Rating: 5 (1 reviews)

Anti-ACVRL1 antibody [C3], C-term used in IHC (Paraffin sections) (IHC-P). GTX100035

Anti-ACVRL1 antibody [C3], C-term used in Western Blot (WB). GTX100035

Cat. No. GTX100035

Reference 1

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human, Mouse
Package	100 μl ($399), 25 μl ($169)

See all ACVRL1 products

View product citations for antibody GTX100035 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:1000-1:10000
IHC-P	1:100-1:1000

Not tested in other applications.

Calculated MW

56 kDa. ( Note )

Positive Control

BCL-1 , HepG2

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide encompassing a sequence within the Intracellular domain of human ACVRL1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1240412

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

activin A receptor like type 1 , ACVRLK1 , ALK-1 , ALK1 , HHT , HHT2 , ORW2 , SKR3 , TSR-I

Cellular Localization

Membrane

Background

This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq]

Database

Gene ID: 94 ACVRL1
UniProt: P37023 ACVRL1

Research Area

DATA IMAGES

GTX100035 IHC-P Image

Immunohistochemical analysis of paraffin-embedded human heart, using Activin A Receptor Type II-like 1(GTX100035) antibody(20 μg/ml).
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX100035 WB Image

Sample (20 ug of whole cell lysate)
A: Hep G2 (GTX27900) membrane extract
7.5% SDS PAGE
GTX100035 diluted at 1:5000

GTX100035 WB Image

Sample (30 ug of whole cell lysate)
A: BCL-1
10% SDS PAGE
GTX100035 diluted at 1:1000

REFERENCE

Application Reference

Chen HW et al. Biochim Biophys Acta 2013; 1829 (12) : 1309-19 A functional genomic approach reveals the transcriptional role of EDD in the expression and function of angiogenesis regulator ACVRL1.

Application : WB

Reactivity : Human

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