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ADAM17 antibody

Anti-ADAM17 antibody used in Western Blot (WB). GTX31632
Anti-ADAM17 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31632
Anti-ADAM17 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31632
Anti-ADAM17 antibody used in Western Blot (WB). GTX31632
Anti-ADAM17 antibody used in Western Blot (WB). GTX31632

Cat No. GTX31632

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, ELISA

Reactivity

Human, Rat
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5 μg/mL
ICC/IF 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

93 kDa. ( Note )

Positive Control

4)HeLa Cell Slide(GTX25529) , Jurkat Cell Lysate(GTX27899) , Raji Cell Lysate(GTX27908)

Specificity/Sensitivity

80 to 130 kDa bands can be detected, which may represent mature protein, precursor, and glycosylated form.

PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

ADAM17 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human ADAM17.The immunogen is located within the last 50 amino acids of ADAM17.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ADAM metallopeptidase domain 17 , ADAM18 , CD156B , CSVP , NISBD , NISBD1 , TACE

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-ADAM17 antibody used in Western Blot (WB). GTX31632

GTX31632 WB Image

WB analysis of HeLa (A, D), Jurkat (B, E) and Raji (C,F) cell lysate in (A-C) the absence or (D-F) the presence of blocking peptide using GTX31632 ADAM17 antibody.
Working concentration : 0.5 μg/ml

Anti-ADAM17 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31632

GTX31632 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX31632 ADAM17 antibody.
Working concentration : 10 μg/ml

Anti-ADAM17 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31632

GTX31632 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX31632 ADAM17 antibody.
Working concentration : 10 μg/ml

Anti-ADAM17 antibody used in Western Blot (WB). GTX31632

GTX31632 WB Image

WB analysis of various sample lysates using GTX31632 ADAM17 antibody.
Loading : 15μg of lysates per lane
Dilution : 0.5 μg/ml

Anti-ADAM17 antibody used in Western Blot (WB). GTX31632

GTX31632 WB Image

WB analysis of HeLa cell or ADAM17 KO cell lysates using GTX31632 ADAM17 antibody.
Dilution : 0.25μg/mL
Loading : 10μg

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339