GeneTex
United States (US)

ADAM19 antibody

Cat No. GTX11552

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1,000
Not tested in other applications.

Calculated MW

105 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.01M PBS, 50% glycerol, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

~1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

synthetic peptide corresponding to the propeptide domain of human ADAM-19.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Adam Metallopeptidase Domain 19,Fksg34,Maddam,Mltnb,Adam19

Background

ADAM19, is a member of the ADAM (a disintegrin and metalloprotease-like domain) family. It has been cloned from mouse and human. ADAM19 was first described in muscle cells as a protein with homology to the fertilins (ADAMs 1 and 2). Initial observations indicated a role for ADAM19 in myoblast fusion, similar to sperm-egg fusion aided by ADAMs 1 and 2. ADAM19 may be important in osteoblast differentiation, as a marker for dendritic cell differentiation, and in the intracellular processing of neuregulin. The ADAMs proteins are structurally similar, possessing a signal sequence, metalloprotease domain (inactive in some ADAMs), disintegrin domain, cysteinrich domain, EGF-like repeat, type-I transmembrane domain, and cytoplasmic domain.

Database

Package List Price ($)
$ 329