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ADAMTS1 antibody

Anti-ADAMTS1 antibody used in Western Blot (WB). GTX12304

Cat. No. GTX12304

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Mouse, Rat
Package
100 μg ($439)
See all ADAMTS1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.5μg/ml
Not tested in other applications.

Calculated MW

106 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.1% Na₂HPO₄, 0.45% NaCl, 2.5% BSA

Preservative

0.025% Thimerosal, 0.025% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of mouse ADAMTS1(956-968aa KHYIDFCTLTQCS), different from the related rat sequence by one amino acid, and from the related human sequence by four amino acids.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 , ADAM-TS1 , ADAMTS , ADAMTS-1 , C3-C5 , METH-1 , METH1

Background

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family and preproprotein that is proteolytically processed to generate a mature protein product. This secreted protein product plays an important role in ovulation, likely through its cleavage of the extracellular matrix component versican. The encoded protein may enhance tumorigenesis in a mouse model of breast cancer. Homozygous knockout mice for this gene exhibit enhanced perinatal lethality, impaired growth and adipose tissue development, and impaired ovulation in females. [provided by RefSeq, Oct 2015]

Database

Research Area

DATA IMAGES

Anti-ADAMTS1 antibody used in Western Blot (WB). GTX12304

GTX12304 WB Image

WB analysis of various samples using GTX12304 ADAMTS1 antibody.
Lane 1 : rat liver tissue lysate at 50ug
Lane 2 : rat heart tissue lysate at 50ug
Lane 3 : rat brain tissue lysate at 50ug
Dilution : 0.5 μg/mL

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Thimerosal.pdf
Package List Price ($)
$ 439