Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Immunogen Sequence: GI # 13569928, sequence 297-446 Recombinant A disintegrin-like and metalloprotease with thrombospondin type 1 motif, 12
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
ADAM metallopeptidase with thrombospondin type 1 motif 12 , PRO4389
Background
This protein is a disintegrin and metalloproteinase with thrombospondin motifs-12 (ADAMTS12). which is a member of the ADAMTS protein family. Members of the family share several distinct protein modules. including a propeptide region. a metalloproteinase domain. a disintegrin-like domain. and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs. and some have unique C-terminal domains. The enzyme encoded by this gene contains 8 TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion.
Database
Research Area