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ADAMTS4 antibody, C-term

Anti-ADAMTS4 antibody, C-term used in Western Blot (WB). GTX81446
Anti-ADAMTS4 antibody, C-term used in Western Blot (WB). GTX81446
Anti-ADAMTS4 antibody, C-term used in Western Blot (WB). GTX81446

Cat No. GTX81446

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB

Reactivity

Human, Mouse
Package
400 μl ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000
Not tested in other applications.

Calculated MW

90 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 705-736 amino acids from the C-terminal region of human ADAMTS4.

Purification

Protein A purified, followed by peptide affinity purification.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ADAM metallopeptidase with thrombospondin type 1 motif 4 , ADAMTS-2 , ADAMTS-4 , ADMP-1

Background

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The expression of this gene is upregulated in arthritic disease and this may contribute to disease progression through the degradation of aggrecan. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

Database

Research Area

DATA IMAGES

Anti-ADAMTS4 antibody, C-term used in Western Blot (WB). GTX81446

GTX81446 WB Image

WB analysis of mouse brain tissue lysate using GTX81446 ADAMTS4 antibody, C-term.
Loading : 20ug
Dilution : 1:1000

Anti-ADAMTS4 antibody, C-term used in Western Blot (WB). GTX81446

GTX81446 WB Image

WB analysis of mouse cerebellum tissue lysate (35ug/lane) using GTX81446 ADAMTS4 antibody, C-term.

Anti-ADAMTS4 antibody, C-term used in Western Blot (WB). GTX81446

GTX81446 WB Image

WB analysis of human lung lysate using GTX81446 ADAMTS4 antibody, C-term.
Loading : 20 μg per lane
Dilution : 1:2000

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 369