ADSL antibody [2D10]

Name: ADSL antibody [2D10]
Brand: GeneTex
SKU: GTX84956
Price: 519.00 USD

Anti-ADSL antibody [2D10] used in Flow cytometry (FACS). GTX84956

Anti-ADSL antibody [2D10] used in Western Blot (WB). GTX84956

Anti-ADSL antibody [2D10] used in IHC (Paraffin sections) (IHC-P). GTX84956

Cat. No. GTX84956

Reference 2

Host	Mouse
Clonality	Monoclonal
Clone Name	2D10
Isotype	IgG1
Application	WB, IHC-P, FACS
Reactivity	Human, Rat, Dog, Monkey
Package	100 μl ($519)

See all ADSL products

View product citations for antibody GTX84956 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:2000
IHC-P	1:150
FACS	1:100

Not tested in other applications.

Calculated MW

55 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.55 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Full length human recombinant protein of human ADSL (NP_000017) produced in HEK293T cell.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_10729929

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

adenylosuccinate lyase , AMPS , ASASE , ASL

Background

Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Database

Gene ID: 158 ADSL
UniProt: P30566 ADSL

Research Area

DATA IMAGES

GTX84956 FACS Image

FACS analysis of HEK293T cells transfected with either ADSL plasmid(Red) or empty vector control plasmid(Blue) using GTX84956 ADSL antibody [2D10].

GTX84956 WB Image

WB analysis of HEK293T cells transfected with ADSL plasmid (Right) or empty vector (Left) for 48 hrs using GTX84956 ADSL antibody [2D10].
Loading : 5 ug per lane

GTX84956 IHC-P Image

IHC-P analysis of human prostate carcinoma tissue using GTX84956 ADSL antibody [2D10].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

GTX84956 IHC-P Image

IHC-P analysis of human kidney carcinoma tissue using GTX84956 ADSL antibody [2D10].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

GTX84956 IHC-P Image

IHC-P analysis of human endometrium adenocarcinoma tissue using GTX84956 ADSL antibody [2D10].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

GTX84956 IHC-P Image

IHC-P analysis of human bladder carcinoma tissue using GTX84956 ADSL antibody [2D10].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

GTX84956 IHC-P Image

IHC-P analysis of human lung carcinoma tissue using GTX84956 ADSL antibody [2D10].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

GTX84956 IHC-P Image

IHC-P analysis of human liver tissue using GTX84956 ADSL antibody [2D10].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

GTX84956 IHC-P Image

IHC-P analysis of human lymphoma tissue using GTX84956 ADSL antibody [2D10].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

GTX84956 IHC-P Image

IHC-P analysis of human ovary adenocarcinoma tissue using GTX84956 ADSL antibody [2D10].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

GTX84956 IHC-P Image

IHC-P analysis of human kidney tissue using GTX84956 ADSL antibody [2D10].
Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100ºC for 10min.

GTX84956 WB Image

WB analysis of various cell lines using GTX84956 ADSL antibody [2D10].
Loading : 35 ug per lane

REFERENCE

Application Reference

Feng X et al. EMBO J 2020; 39 (5) : e102541 UHMK1 promotes gastric cancer progression through reprogramming nucleotide metabolism.

Zhou Q et al. J Exp Med 2020; 217 (8) Targeting CLK3 inhibits the progression of cholangiocarcinoma by reprogramming nucleotide metabolism.

Reactivity : Human

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REVIEW

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Application Reference

Feng X et al. EMBO J 2020; 39 (5):e102541 UHMK1 promotes gastric cancer progression through reprogramming nucleotide metabolism.

Zhou Q et al. J Exp Med 2020; 217 (8) Targeting CLK3 inhibits the progression of cholangiocarcinoma by reprogramming nucleotide metabolism.

Reactivity : Human

SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf

Package

List Price ($)

100 μl

$ 519

Qty

ADSL antibody [2D10]

Cat. No. GTX84956

Host

Clonality

Clone Name

Isotype

Application

Reactivity

APPLICATION

Application Note

Calculated MW

PROPERTIES

Form

Buffer

Preservative

Storage

Concentration

Antigen Species

Immunogen

Purification

Conjugation

RRID

Note

TARGET

Synonyms

Background

Database

Research Area

DATA IMAGES

GTX84956 FACS Image

GTX84956 WB Image

GTX84956 IHC-P Image

GTX84956 IHC-P Image

GTX84956 IHC-P Image

GTX84956 IHC-P Image

GTX84956 IHC-P Image

GTX84956 IHC-P Image

GTX84956 IHC-P Image

GTX84956 IHC-P Image

GTX84956 IHC-P Image

GTX84956 WB Image

REFERENCE

Application Reference

REVIEW

Product

Research

Support

Company

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All products are for research use only—Not for use in diagnostic or therapeutic applications.