GeneTex
United States (US)

AGRP antibody, C-term

GTX89559_142_IHC-Fr_18121411_533.jpg

Cat No. GTX89559

Host Goat
Clonality Polyclonal
Isotype IgG
Application IHC-Fr
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-Fr 0.05-0.1μg/ml

Note :

IHC-Fr
Human Hypothalamus shows staining of a group of neuronal cell bodies in the human infundibular (arcuate) nucleus and their varicose axons.

Not tested in other applications.

Calculated MW

14 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89559-PEP).

Specificity/Sensitivity

This antibody is expected to recognise both reported isoforms (as represented by NP_001129; NP_015531)

Predict Reactivity

Dog, Pig(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence CRKLGTAMNPCSRT, from the C Terminus of the protein sequence according to NP_001129.1; NP_015531.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Agouti Related Neuropeptide,Agrt,Art,Asip2,Agrp

Background

This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009]

Database

DATA IMAGES
GTX89559_142_IHC-Fr_18121411_533.jpg

GTX89559 IHC-Fr Image

IHC-Fr analysis of PFA-perfused human hypothalamus using GTX89559 AGRP antibody, C-term.
Antigen retrieval : citrate buffer pH 6 at 80C for 30min
Dilution : 0.05µg/ml

Package List Price ($)
$ 329