APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 - 2 μg/mL |
| 2.5 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Mouse Kidney Tissue Lysate(GTX27936)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
AGTR1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human AGTR1.The immunogen is located within amino acids 210 - 260 of AGTR1.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
angiotensin II receptor type 1 , AG2S , AGTR1B , AT1 , AT1AR , AT1B , AT1BR , AT1R , AT2R1 , HAT1R
Cellular Localization
Cell membrane; Multi-pass membrane protein
Background
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
Database
Research Area
DATA IMAGES
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GTX31793 IHC-P Image
IHC-P analysis of mouse kidney tissue using GTX31793 AGTR1 antibody.
Working concentration : 20 μg/ml
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GTX31793 IHC-P Image
IHC-P analysis of mouse kidney tissue using GTX31793 AGTR1 antibody.
Working concentration : 2.5 μg/ml
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GTX31793 WB Image
WB analysis of mouse kidney tissue lysate using GTX31793 AGTR1 antibody.
Dilution : 1μg/ml (Lane A) and 2 μg/ml (Lane B)
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GTX31793 IHC-P Image
IHC-P analysis of mouse kidney tissue using GTX31793 AGTR1 antibody.
Working concentration : 2.5 μg/ml
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GTX31793 WB Image
WB analysis of mouse kidney tissue lysate using GTX31793 AGTR1 antibody.
Working concentration : Lane A: 1 μg/ml, Lane B: 2 μg/ml
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REFERENCE
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REVIEW
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