Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
Synthetic peptide corresponding to the C-terminal amino acids C(349)RKSSSLREMETFVS(363) of AGTR2
Purification
Unpurified
Conjugation
Unconjugated
RRID
AB_11163809
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
angiotensin II receptor type 2 , AT2 , ATGR2 , MRX88
Cellular Localization
Cell membrane; Multi-pass membrane protein
Background
The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked cognitive disability. [provided by RefSeq, Jan 2010]
IHC-P analysis of tissue using GTX79393 AGTR2 antibody.
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GTX79393 WB Image
WB analysis of HEK293 cells overexpressing AT2 (AGTR2) protein using GTX79393 AGTR2 antibody.
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GTX79393 ICC/IF Image
ICC/IF analysis of HEK293 cells using GTX79393 AGTR2 antibody. Panel e is a no primary antibody control. Green : Primary antibody Blue : Nuclei Red : Actin Fixation : 4% paraformaldehyde Permeabilization : 0.1% Triton X-100 for 10 minute Dilution : 1:250 dilution in 0.1% BSA and incubated for 3 hours at room temperature