GeneTex
United States (US)

AIPL1 antibody

GTX17024_2334_WB_20180221_18121410_664.jpg
GTX17024_725_IHC-P_20180221_18121410_202.jpg
GTX17024_726_IHC-P_20180221_18121410_498.jpg

Cat No. GTX17024

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

44 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Human Brain Tissue Lysate(GTX27918)
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Aipl1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human Aipl1.The immunogen is located within amino acids 290 - 340 of Aipl1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Aryl Hydrocarbon Receptor Interacting Protein Like 1,Aipl2,Lca4,Aipl1

Background

Leber congenital amaurosis (LCA) accounts for at least 5% of all inherited retinal disease and is the most severe inherited retinopathy with the earliest age of onset. Individuals affected with LCA are diagnosed at birth or in the first few months of life with severely impaired vision or blindness, nystagmus and an abnormal or flat electroretinogram. The photoreceptor/pineal -expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, was mapped within the LCA4 candidate region. The protein contains three tetratricopeptide motifs, consistent with nuclear transport or chaperone activity. AIPL1 mutations may cause approximately 20% of recessive LCA. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX17024_2334_WB_20180221_18121410_664.jpg

GTX17024 WB Image

WB analysis of human brain tissue lysate using GTX17024 AIPL1 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

GTX17024_725_IHC-P_20180221_18121410_202.jpg

GTX17024 IHC-P Image

IHC-P analysis of human brain tissue using GTX17024 AIPL1 antibody.
Working concentration : 2.5 μg/ml

GTX17024_726_IHC-P_20180221_18121410_498.jpg

GTX17024 IHC-P Image

IHC-P analysis of human brain tissue using GTX17024 AIPL1 antibody.
Working concentration : 20 μg/ml

Package List Price ($)
$ 329