GeneTex
United States (US)

AIRE antibody

GTX30036_20180530_ICCIF_18121410_490.jpg
GTX30036_20180530_WB_18121410_347.jpg

Cat No. GTX30036

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

58 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

A synthetic peptide of human AIRE

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

PGA1 Antibody , APSI Antibody , APS1 Antibody , APECED Antibody , AIRE1 Antibody

Background

This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]

Database

DATA IMAGES
GTX30036_20180530_ICCIF_18121410_490.jpg

GTX30036 ICC/IF Image

ICC/IF analysis of A549 cell using GTX30036 AIRE antibody.
Blue : DAPI

GTX30036_20180530_WB_18121410_347.jpg

GTX30036 WB Image

WB analysis of various samples using GTX30036 AIRE antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 319