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AIRE antibody

Anti-AIRE antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30036
Anti-AIRE antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30036
Anti-AIRE antibody used in Western Blot (WB). GTX30036
Anti-AIRE antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30036

Cat No. GTX30036

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF

Reactivity

Human, Mouse, Rat
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide of human AIRE

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

autoimmune regulator , AIRE1 , APECED , APS1 , APSI , PGA1

Cellular Localization

Nucleus,Cytoplasm

Background

This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]

Database

DATA IMAGES

Anti-AIRE antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30036

GTX30036 ICC/IF Image

ICC/IF analysis of C6 cells using GTX30036 AIRE antibody.
Blue : DAPI
Dilution : 1:100

Anti-AIRE antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30036

GTX30036 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX30036 AIRE antibody.
Blue : DAPI
Dilution : 1:100

Anti-AIRE antibody used in Western Blot (WB). GTX30036

GTX30036 WB Image

WB analysis of various sample lysates using GTX30036 AIRE antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-AIRE antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30036

GTX30036 ICC/IF Image

ICC/IF analysis of NIH/3T3 cells using GTX30036 AIRE antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339