*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Synthetic peptide: 1:8,000
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human AKAP10. The exact sequence is proprietary.
Purified by antigen-affinity chromatography.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
D-AKAP2 antibody, MGC9414 antibody, PRKA10 antibody, AKAP10 antibody, dual specificity A kinase-anchoring protein 2 antibody, D-AKAP-2 antibody, a kinase anchor protein 10, mitochondrial antibody, A-kinase anchor protein 10, mitochondrial antibody, dual-specificity A-kinase anchoring protein 2 antibody, protein kinase A anchoring protein 10 antibody, protein kinase A-anchoring protein 10 antibody, AKAP-10 antibody, mitochondrial A kinase PPKA anchor protein 10 antibody, A kinase (PRKA) anchor protein 10 antibody
Mitochondrion , Membrane , Cytoplasm
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction. [provided by RefSeq]