PBS, 0.08% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
A-kinase anchoring protein 12 , AKAP12A , AKAP12B , AKAP12G
SSeCKS (Src Suppressed C Kinase Substrate) is a major protein kinase C substrate with tumor suppressor activity in models of src- and ras-induced oncogenic transformation. SSeCKS regulates actin-based cytoskeletal and tissue architecture, as well as kinases such as protein kinase C (PKC), protein kinase A (PKA) and calmodulin. Additionally, SSeCKS, has been implicated in the formation of migratory processes and cell migration during embryogenesis. Rat SSeCKS shares extensive homology with human Gravin, an autoantigen in myasthenia gravis that encodes kinase scaffolding functions and whose expression pattern in fibroblasts and nerves suggests a role in cell motility.