AKR1B10 antibody [N3C3]

Name: AKR1B10 antibody [N3C3]
Brand: GeneTex
SKU: GTX116651
Price: 399.00 USD
Rating: 5 (2 reviews)

Anti-AKR1B10 antibody [N3C3] used in Western Blot (WB). GTX116651

Anti-AKR1B10 antibody [N3C3] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX116651

Cat. No. GTX116651

Reference 1

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF
Reactivity	Human
Package	100 μl ($399), 25 μl ($169)

See all AKR1B10 products

View product citations for antibody GTX116651 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500-1:3000
ICC/IF	1:100-1:1000

Not tested in other applications.

Calculated MW

36 kDa. ( Note )

Positive Control

HCT116

Product Note

Knockdown/Knockout validation was supported by customer review data.

Predict Reactivity

Mouse, Rat, Rabbit, Bovine, Chicken(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.34 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human AKR1B10. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_10615515

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

aldo-keto reductase family 1 member B10 , AKR1B11 , AKR1B12 , ALDRLn , ARL-1 , ARL1 , HIS , HSI

Cellular Localization

Cytoplasm

Background

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq]

Database

Gene ID: 57016 AKR1B10
UniProt: O60218 AKR1B10

Research Area

DATA IMAGES

GTX116651 WB Image

Sample (30 ug of whole cell lysate)
A: HCT116
10% SDS PAGE
GTX116651 diluted at 1:1000

GTX116651 ICC/IF Image

Immunofluorescence analysis of methanol-fixed HeLa, using AKR1B10(GTX116651) antibody at 1:200 dilution.

REFERENCE

Application Reference

Choi EJ et al. Oncogene 2017; (Epub) A clinical drug library screen identifies * propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer.

Application : WB

Reactivity : Human

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REVIEW