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AKR7A2 antibody

Anti-AKR7A2 antibody used in Western Blot (WB). GTX55500
Anti-AKR7A2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55500
Anti-AKR7A2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55500

Cat. No. GTX55500

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all AKR7A2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:10 - 1:100
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 100-359 of human AKR7A2 (NP_003680.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

aldo-keto reductase family 7 member A2 , AFAR , AFAR1 , AFB1-AR1 , AKR7

Cellular Localization

Golgi apparatus,Cytoplasm

Background

The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Database

Research Area

DATA IMAGES

Anti-AKR7A2 antibody used in Western Blot (WB). GTX55500

GTX55500 WB Image

WB analysis of various sample lysates using GTX55500 AKR7A2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-AKR7A2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55500

GTX55500 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX55500 AKR7A2 antibody.
Dilution : 1:100

Anti-AKR7A2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55500

GTX55500 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX55500 AKR7A2 antibody.
Blue : DAPI

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399