APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| Assay dependent |
| Assay dependent |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS, 10% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The clone AT2C10 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ALDH4 protein.
Purification
Protein A Purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
aldehyde dehydrogenase 2 family member , ALDH2 , ALDHE2 , ALDHI , ALDM , aldehyde dehydrogenase 2 family (mitochondrial)
Cellular Localization
Mitochondrion matrix
Background
This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2016]
Database
Research Area
DATA IMAGES
![Anti-ALDH2 antibody [AT2C10] used in Western Blot (WB). GTX57696](/templates/default/js/lightbox/images/loading.gif "Anti-ALDH2 antibody [AT2C10] used in Western Blot (WB). GTX57696")
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GTX57696 WB Image
WB analysis of various samples using GTX57696 ALDH2 antibody.
Lane 1 : 293T cell lysate
Lane 2 : ALDH2 transfected 293T cell lysate
Loading : 40 μg
Dilution : 1:500
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GTX57696 ICC/IF Image
ICC/IF analysis of A549 cells using GTX57696 ALDH2 antibody.
Green: Primary antibody
Dilution: 1:100
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GTX57696 WB Image
WB analysis of various samples using GTX57696 ALDH2 antibody.
Lane 1 : HepG2 whole cell lysate
Lane 2 : Mouse liver tissue lysate
Lane 3 : Mouse lung tissue lysate
Dilution : 1:1000
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REFERENCE
There are currently no references for ALDH2 antibody [AT2C10] (GTX57696). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for ALDH2 antibody [AT2C10] (GTX57696). Be the first to share your experience with this product.
![Anti-ALDH2 antibody [AT2C10] used in Western Blot (WB). GTX57696](/upload/website/prouct_img/small/GTX57696/GTX57696_20200204_WB2_w_23061123_181.webp "Anti-ALDH2 antibody [AT2C10] used in Western Blot (WB). GTX57696")
![Anti-ALDH2 antibody [AT2C10] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX57696](/upload/website/prouct_img/small/GTX57696/GTX57696_20200204_IF_w_23061123_873.webp "Anti-ALDH2 antibody [AT2C10] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX57696")
![Anti-ALDH2 antibody [AT2C10] used in Western Blot (WB). GTX57696](/upload/website/prouct_img/small/GTX57696/GTX57696_20200204_WB1_w_23061123_630.webp "Anti-ALDH2 antibody [AT2C10] used in Western Blot (WB). GTX57696")
![Anti-ALDH2 antibody [AT2C10] used in Western Blot (WB). GTX57696](/upload/website/prouct_img/normal/GTX57696/GTX57696_20200204_WB2_w_23061123_181.webp "Anti-ALDH2 antibody [AT2C10] used in Western Blot (WB). GTX57696")
![Anti-ALDH2 antibody [AT2C10] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX57696](/upload/website/prouct_img/normal/GTX57696/GTX57696_20200204_IF_w_23061123_873.webp "Anti-ALDH2 antibody [AT2C10] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX57696")
![Anti-ALDH2 antibody [AT2C10] used in Western Blot (WB). GTX57696](/upload/website/prouct_img/normal/GTX57696/GTX57696_20200204_WB1_w_23061123_630.webp "Anti-ALDH2 antibody [AT2C10] used in Western Blot (WB). GTX57696")