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ALDH2 antibody

Anti-ALDH2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55502
Anti-ALDH2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55502
Anti-ALDH2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55502
Anti-ALDH2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55502
Anti-ALDH2 antibody used in Western Blot (WB). GTX55502

Cat. No. GTX55502

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

56 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-380 of human ALDH2 (NP_000681.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

aldehyde dehydrogenase 2 family member , ALDH-E2 , ALDHI , ALDM

Cellular Localization

Mitochondrion matrix

Background

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2016]

Database

Research Area

DATA IMAGES

Anti-ALDH2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55502

GTX55502 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX55502 ALDH2 antibody.

Anti-ALDH2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55502

GTX55502 IHC-P Image

IHC-P analysis of rat liver tissue using GTX55502 ALDH2 antibody.
Dilution : 1:100

Anti-ALDH2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55502

GTX55502 IHC-P Image

IHC-P analysis of human esophageal cancer tissue using GTX55502 ALDH2 antibody.
Dilution : 1:100

Anti-ALDH2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55502

GTX55502 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX55502 ALDH2 antibody.
Dilution : 1:100

Anti-ALDH2 antibody used in Western Blot (WB). GTX55502

GTX55502 WB Image

WB analysis of various sample lysates using GTX55502 ALDH2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399