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ALDH3A1 antibody

Anti-ALDH3A1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30042
Anti-ALDH3A1 antibody used in Western Blot (WB). GTX30042

Cat. No. GTX30042

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all ALDH3A1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ALDH3A1 (NP_001128640.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

aldehyde dehydrogenase 3 family member A1 , ALDH3 , ALDHIII

Cellular Localization

Cytoplasm

Background

Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]

Database

  • Gene ID: 218 ALDH3A1
  • UniProt: P30838 ALDH3A1

Research Area

DATA IMAGES

Anti-ALDH3A1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30042

GTX30042 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX30042 ALDH3A1 antibody.
Blue : DAPI

Anti-ALDH3A1 antibody used in Western Blot (WB). GTX30042

GTX30042 WB Image

WB analysis of various sample lysates using GTX30042 ALDH3A1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

Application Reference

Li M et al. Nat Commun 2024; 15 (1) : 256 The single-cell transcriptomic atlas and RORA-mediated 3D epigenomic remodeling in driving corneal epithelial differentiation.
Wang B et al. Curr Issues Mol Biol 2023; 45 (12) : 10121-10130 NRG1 Regulates Proliferation, Migration and Differentiation of Human Limbal Epithelial Stem Cells.
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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399