GeneTex
United States (US)

ALDH6A1 antibody

GTX103405_WB_19011506_852.jpg
GTX103405_39918_IHC_19011506_651.jpg
GTX103405_39918_WB_M_Liver_19011506_645.jpg
GTX103405_39918_IHC_M_19011506_595.jpg

Cat No. GTX103405

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

Positive Control

HepG2 , mouse liver

Predict Reactivity

Rat, Zebrafish, Bovine, Xenopus laevis(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human ALDH6A1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Aldehyde Dehydrogenase 6 Family Member A1,Mmsadha,Mmsdh,Aldh6A1

Cellular Localization

Mitochondrion

Background

This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX103405_WB_19011506_852.jpg

GTX103405 WB Image

Sample(30 ug whole cell lysate)
A:Hep G2(GTX27900)
7.5% SDS PAGE
GTX103405 diluted at 1:500

GTX103405_39918_IHC_19011506_651.jpg

GTX103405 IHC-P Image

ALDH6A1 antibody detects ALDH6A1 protein at mitochondria on human liver carcinoma by immunohistochemical analysis.
Sample: Paraffin-embedded liver carcinoma.
ALDH6A1 antibody (GTX103405) dilution: 1:250.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX103405_39918_WB_M_Liver_19011506_645.jpg

GTX103405 WB Image

Sample (50 ug of whole cell lysate)
A: Mouse liver
7.5% SDS PAGE
GTX103405 diluted at 1:1000

GTX103405_39918_IHC_M_19011506_595.jpg

GTX103405 IHC-P Image

ALDH6A1 antibody detects ALDH6A1 protein at cytosol on mouse stomach by immunohistochemical analysis.
Sample: Paraffin-embedded mouse stomach.
ALDH6A1 antibody (GTX103405) dilution: 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169