GeneTex
United States (US)

ALIX antibody

GTX64925_20180530_IHC-P_1_18121411_525.jpg
GTX64925_20180530_IHC-P_18121411_540.jpg
GTX64925_20180530_IHC-P_2_18121411_299.jpg
GTX64925_20180530_WB_18121411_684.jpg

Cat No. GTX64925

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:200 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

96 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 1-180 of human PDCD6IP (NP_037506.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

AIP1 Antibody , PDCD6IP Antibody , DRIP4 Antibody , HP95 Antibody

Background

This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012]

Database

Research Area

DATA IMAGES
GTX64925_20180530_IHC-P_1_18121411_525.jpg

GTX64925 IHC-P Image

IHC-P analysis of human stomach tissue using GTX64925 ALIX antibody.
Dilution : 1:100

GTX64925_20180530_IHC-P_18121411_540.jpg

GTX64925 IHC-P Image

IHC-P analysis of human prostate tissue using GTX64925 ALIX antibody.
Dilution : 1:100

GTX64925_20180530_IHC-P_2_18121411_299.jpg

GTX64925 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX64925 ALIX antibody.
Dilution : 1:100

GTX64925_20180530_WB_18121411_684.jpg

GTX64925 WB Image

WB analysis of various samples using GTX64925 ALIX antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 319