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ALOX15B antibody

Anti-ALOX15B antibody used in Western Blot (WB). GTX33001
Anti-ALOX15B antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33001

Cat. No. GTX33001

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all ALOX15B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human ALOX15B (NP_001132.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

arachidonate 15-lipoxygenase type B , 15-LOX-2

Cellular Localization

Cell membrane,Cytoplasm, cytoskeleton

Background

This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 247 ALOX15B
  • UniProt: O15296 ALOX15B

Research Area

DATA IMAGES

Anti-ALOX15B antibody used in Western Blot (WB). GTX33001

GTX33001 WB Image

WB analysis of various sample lysates using GTX33001 ALOX15B antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-ALOX15B antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33001

GTX33001 ICC/IF Image

ICC/IF analysis of MCF7 cells using GTX33001 ALOX15B antibody.

REFERENCE

Application Reference

Fan Y et al. Cell Death Dis 2022; 13 (11) : 1000 Identification of a group of bisbenzylisoquinoline (BBIQ) compounds as ferroptosis inhibitors.
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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399