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ALS2CR2 antibody

Anti-ALS2CR2 antibody used in Western Blot (WB). GTX31282
Anti-ALS2CR2 antibody used in IHC (Paraffin sections) (IHC-P). GTX31282

Cat No. GTX31282

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, ELISA

Reactivity

Human, Mouse, Rat
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Human Brain Tissue Lysate(GTX27918)

PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

ALS2CR2 antibody was raised against a synthetic peptide corresponding to amino acids near the center of human ALS2CR2.The immunogen is located within amino acids 280 - 330 of ALS2CR2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

STE20 related adaptor beta , ALS2CR2 , CALS-21 , ILPIP , ILPIPA , PAPK , PRO1038

Cellular Localization

Nucleus,Cytoplasm

Background

This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

Database

Research Area

DATA IMAGES

Anti-ALS2CR2 antibody used in Western Blot (WB). GTX31282

GTX31282 WB Image

WB analysis of human brain tissue lysate using GTX31282 ALS2CR2 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Anti-ALS2CR2 antibody used in IHC (Paraffin sections) (IHC-P). GTX31282

GTX31282 IHC-P Image

IHC-P analysis of human brain tissue using GTX31282 ALS2CR2 antibody.
Working concentration : 10 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339