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AMACR antibody [AMACR/4572R]

Anti-AMACR antibody [AMACR/4572R] used in IHC (Paraffin sections) (IHC-P). GTX02586
Anti-AMACR antibody [AMACR/4572R] used in IHC (Paraffin sections) (IHC-P). GTX02586
Anti-AMACR antibody [AMACR/4572R] used in Western Blot (WB). GTX02586

Cat. No. GTX02586

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 AMACR/4572R

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all AMACR products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2 μg/ml
ICC/IF 1-2 μg/ml
IHC-P 1-2 μg/ml

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

42 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human AMACR protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

alpha-methylacyl-CoA racemase , AMACRD , CBAS4 , P504S , RACE , RM

Cellular Localization

Mitochondrion

Background

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]

Database

Research Area

DATA IMAGES

Anti-AMACR antibody [AMACR/4572R] used in IHC (Paraffin sections) (IHC-P). GTX02586

GTX02586 IHC-P Image

IHC-P analysis of human prostate carcinoma section using GTX02586 AMACR antibody [AMACR/4572R].

Anti-AMACR antibody [AMACR/4572R] used in IHC (Paraffin sections) (IHC-P). GTX02586

GTX02586 IHC-P Image

IHC-P analysis of human prostate carcinoma section using GTX02586 AMACR antibody [AMACR/4572R].

Anti-AMACR antibody [AMACR/4572R] used in Western Blot (WB). GTX02586

GTX02586 WB Image

WB analysis of human kidney tissue lysate using GTX02586 AMACR antibody [AMACR/4572R].

REFERENCE

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REVIEW

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Package List Price ($)
$ 529